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4-Methylbenzylidene camphor
$65 – $370
Products Details
Product Description
– 4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy[1][2].
Web ID
– HY-17587
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C18H22O
References
– [1]Changwon Yang, et al. 4-Methylbenzylidene-camphor inhibits proliferation and induces reactive oxygen species-mediated apoptosis of human trophoblast cells. Reprod Toxicol. 2019 Mar:84:49-58.|[2]Margret Schlumpf, et al. Developmental toxicity of UV filters and environmental exposure: a review. Int J Androl. 2008 Apr;31(2):144-51.
CAS Number
– 36861-47-9
Molecular Weight
– 254.37
Compound Purity
– 99.87
SMILES
– CC1(C)[C@@H]2CC[C@]1(C)C(/C2=CC3=CC=C(C)C=C3)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL
Target
– Akt;Apoptosis;ERK;PI3K
Isoform
– Akt;ERK1;ERK2;PI3K
Pathway
– Apoptosis;MAPK/ERK Pathway;PI3K/Akt/mTOR;Stem Cell/Wnt
Product type
– Reference compound
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