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4-CPPC
Price range: 82 CAD through 3,072 CAD
Products Details
Product Description
– 4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Web ID
– T38293
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H9NO6
References
– Tilstam, P.V., Pantouris, G., Corman, M., et al.A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activityJ. Biol. Chem.294(49)18522-18531(2019)
CAS Number
– 29553-70-6
Molecular Weight
– C14H9NO6
Compound Purity
– 0.971
SMILES
– OC(=O)C1=CC=CC(=C1)C1=CC(=NC=C1C(O)=O)C(O)=O
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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