3-Phenyltoxoflavin

$99$1,980

Products Details

Product Description

– 3-Phenyltoxoflavin, a derivative of Toxoflavin, is an Hsp90 inhibitor, with a Kd of 585 nM for the interaction of Hsp90-TPR2A. 3-Phenyltoxoflavin has anti-cancer activity[1][2].

Web ID

– HY-125759

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C13H11N5O2

References

– [1]Yi F, et, al. A novel class of small molecule inhibitors of Hsp90. ACS Chem Biol. 2008 Oct 17;3(10):645-54.|[2]Koh S, et, al. A novel light-dependent selection marker system in plants. Plant Biotechnol J. 2011 Apr;9(3):348-58.

CAS Number

– 32502-63-9

Molecular Weight

– 269.26

Compound Purity

– 99.86

SMILES

– O=C(C1=NC(C2=CC=CC=C2)=NN(C)C1=N3)N(C)C3=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 7.14 mg/mL (ultrasonic)

Target

– HSP

Isoform

– HSP90

Pathway

– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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