(2R,5S)-Ritlecitinib

$180$1,490

Products Details

Product Description

– (2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective JAK3 inhibitor (IC50=144.8 nM) extracted from patent US20150158864A1, example 68[1].

Web ID

– HY-100754B

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C15H19N5O

References

– [1]Atli Thorarensen, et al. Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyr-rolo[2,3-d]pyridinyl acrylamides. US20150158864A1.

CAS Number

– 1792180-79-0

Molecular Weight

– 285.34

Compound Purity

– 98.83

SMILES

– C[C@@H]1CC[C@@H](CN1C(C=C)=O)NC2=C3C=CNC3=NC=N2

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 220 mg/mL (ultrasonic)

Target

– JAK

Isoform

– JAK3

Pathway

– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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