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2,5-Dihydroxyacetophenone
Price range: 59 CAD through 197 CAD
Products Details
Product Description
– 1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPKs, it also can potentiate the pro-apoptotic and anti-proliferative effects of bortezomib in U266 cells. 3. 2,5-Dihydroxyacetophenone (Quinacetophenone) has anti-inflammatory activity in activated macrophages, raising the possibility that this compound has a therapeutic potential for inflammatory conditions. 4. 2,5-Dihydroxyacetophenone (Quinacetophenone) is an uncompetitive inhibitor of murine tyrosinase (K(I) 0.28mm), it strongly inhibits both melanogenesis and cellular tyrosinase activity in vitro in 3-isobutyl-1-methylxanthin-stimulated B16 mouse melanoma cells or in vivo in zebrafish and mouse models.
Web ID
– TCS2170
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C8H8O3
References
– Han Y , Jung H W , Lee J Y , et al. 2,5-Dihydroxyacetophenone Isolated from Rehmanniae Radix Preparata Inhibits Inflammatory Responses in Lipopolysaccharide-Stimulated RAW264.7 Macrophages[J]. Journal of Medicinal Food, 2012, 15(6):505-510.
CAS Number
– 490-78-8
Molecular Weight
– C8H8O3
Compound Purity
– 0.9991
SMILES
– CC(=O)C1=CC(O)=CC=C1O
Pathway
– Proteases/Proteasome|||NF-κB|||MAPK
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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