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2,2,5,7,8-Pentamethyl-6-Chromanol

SKU T14008-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 46 CAD through 123 CAD

Products Details

Product Description

– 2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the antioxidant component of vitamin E (α-tocopherol) and exhibits significant androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines.

Web ID

– T14008

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H20O2

Citations

– 1. Bi G, Liang J, Shan G, et al.Retinol saturase mediates retinoid metabolism to impair a ferroptosis defense system in cancer cells.Cancer Research.2023: CAN-22-3977.

References

– Kyriakopoulos CE, et al. A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin E 2,2,5,7,8-pentamethyl-6-chromanol (APC-100) in men with advanced prostate cancer. Invest New Drugs. 2016 Apr;34(2):225-30.

CAS Number

– 950-99-2

Molecular Weight

– C14H20O2

Compound Purity

– 0.993

SMILES

– Cc1c(C)c2OC(C)(C)CCc2c(C)c1O

Target

– Others

Pathway

– Endocrinology/Hormones

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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