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Product Description
– 2’-O-Methyl-5-iodouridine (5-Iodo-2′-O-methyluridine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Web ID
– HY-W340190
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C10H13IN2O6
References
– [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
CAS Number
– 34218-84-3
Molecular Weight
– 384.12
SMILES
– O[C@H]1[C@@H](OC)[C@H](N2C(NC(C(I)=C2)=O)=O)O[C@@H]1CO
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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