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(16R)-Epothilone D
$65 – $600
Products Details
Product Description
– (16R)-Epothilone D is the inactive isomer of Epothilone D (HY-15278), and can be used as an experimental control. Epothilone D (KOS 862) is a potent microtubule stabilizer.
Web ID
– HY-15278A
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C27H41NO5S
References
– [1]Brunden KR, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy.
J Neurosci. 2010 Oct 13;30(41):13861-6.|[2]Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma.
Invest New Drugs. 2012 Dec;30(6):2294-302.
Molecular Weight
– 491.68
Compound Purity
– 95.11
SMILES
– O=C(C[C@H](O)C1(C)C)O[C@@H](/C(C)=C/C2=CSC(C)=N2)C/C=C(C)CCC[C@H](C)[C@H](O)[C@@H](C)C1=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
