14,15-EE-5(Z)-E

SKU T36150-25 μg Category Brand:

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Products Details

Product Description

– Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-5(Z)-E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle. Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5(Z)-E at a concentration of 10 μM. 14,15-EE-5(Z)-E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation.

Web ID

– T36150

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H36O3

CAS Number

– 519038-92-7

Molecular Weight

– C20H36O3

SMILES

– CCCCC[C@@H]1O[C@@H]1CCCCCCCC=C/CCCC(O)=O

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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