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12-Ethyl-9-hydroxycamptothecin
$31 – $210
Products Details
Product Description
– 12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1].
Web ID
– HY-N2063
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Molecular Formula
– C22H20N2O5
References
– [1]Luzzio MJ, et al. Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I. J Med Chem. 1995;38(3):395-401.
CAS Number
– 119577-28-5
Molecular Weight
– 392.40
Compound Purity
– 98.90
SMILES
– O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(O)C=CC(CC)=C5N=C4C3=C2)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– Topoisomerase
Pathway
– Cell Cycle/DNA Damage
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
