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Products Details
Product Description
– 1,1,1-Trifluoroethyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 1,1,1-Trifluoroethyl-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-140887
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C13H21F3O5
References
– [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
CAS Number
– 1817735-37-7
Molecular Weight
– 314.30
SMILES
– C#CCOCCOCCOCCOCCOCC(F)(F)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PROTAC Linkers
Isoform
– PEG Linkers
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
