10-Nitrolinoleic acid

$113

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Products Details

Product Description

– 10-Nitrolinoleic acid is a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist. 10-Nitrolinoleic acid competes with [3H]Rosiglitazone for binding to PPAR-γ, with an IC50 of 0.22 μM[1].

Web ID

– HY-113473

Shipping

– Room temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C18H31NO4

References

– [1]Dunny E, et, al. Stereocontrolled synthesis of the PPAR-gamma agonist 10-nitrolinoleic acid. J Org Chem. 2010 Aug 6;75(15):5334-6.

CAS Number

– 774603-04-2

Molecular Weight

– 325.44

SMILES

– CCCCC/C=CC/C([N+]([O-])=O)=CCCCCCCCC(O)=O

Clinical Information

– No Development Reported

Research Area

– Cancer; Metabolic Disease; Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– PPAR

Isoform

– PPARγ

Pathway

– Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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