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10-Nitrolinoleic acid
SKU
HY-113473-100μg
Category Reference compound
Tags Cancer; Metabolic Disease; Inflammation/Immunology, Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor, PPAR
$113
Only 1000 item(s) left in stock.
Products Details
Product Description
– 10-Nitrolinoleic acid is a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist. 10-Nitrolinoleic acid competes with [3H]Rosiglitazone for binding to PPAR-γ, with an IC50 of 0.22 μM[1].
Web ID
– HY-113473
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C18H31NO4
References
– [1]Dunny E, et, al. Stereocontrolled synthesis of the PPAR-gamma agonist 10-nitrolinoleic acid. J Org Chem. 2010 Aug 6;75(15):5334-6.
CAS Number
– 774603-04-2
Molecular Weight
– 325.44
SMILES
– CCCCC/C=CC/C([N+]([O-])=O)=CCCCCCCCC(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Metabolic Disease; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– PPAR
Isoform
– PPARγ
Pathway
– Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.