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10-Methoxycamptothecin
$57 – $190
Products Details
Product Description
– 10-Methoxycamptothecin is a natural bioactive derivative of camptothecin (CPT) isolated from Camptotheca acuminata, and has been confirmed to possess high anti-cancer properties. 10-Methoxycamptothecin has higher cytotoxicity than 10-hydroxycamptothecin by testing antitumor activity against 2774 cell lines[1].
Web ID
– HY-N0446
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H18N2O5
References
– [1]Zheng J, et al. Development and validation of a RP-HPLC method with fluorescence detection for simultaneous determination of 10-methoxycamptothecin and its metabolite 10-hydroxycamptothecin in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Aug 15;903:81-7.
CAS Number
– 19685-10-0
Molecular Weight
– 378.38
Compound Purity
– 99.03
SMILES
– O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=CC(OC)=CC=C5N=C4C3=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 8.33 mg/mL (ultrasonic)
Target
– ADC Cytotoxin
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
