1′-Hydroxy bufuralol

$760$1,220

Products Details

Product Description

– 1′-Hydroxy bufuralol, the main metabolite of bufuralol, can reflect CYP2D activity[1].

Web ID

– HY-122277

Storage Temperature

– -20°C (Powder, sealed storage, away from moisture)

Shipping

– Blue Ice

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C16H23NO3

References

– [1]Evangelos P Daskalopoulos, et al. Dâ‚‚-dopaminergic receptor-linked pathways: critical regulators of CYP3A, CYP2C, and CYP2D. Mol Pharmacol. 2012 Oct;82(4):668-78.|[2]H Yamazaki, et al. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes. Mol Pharmacol. 1994 Sep;46(3):568-77.

CAS Number

– 57704-16-2

Molecular Weight

– 277.36

Compound Purity

– 97.0

SMILES

– CC(C1=C2OC(C(CNC(C)(C)C)O)=CC2=CC=C1)O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Cytochrome P450

Isoform

– CYP2

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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