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σ1 Receptor antagonist-1
$50 – $935
Products Details
Product Description
– σ1 Receptor antagonist-1 is a highly potent and selective sigma 1 receptor antagonist (pKi=10.28). σ1 Receptor antagonist-1 inhibits cell growth, arrests cell cycle at G0/G1 phase and induces apoptosis of MCF-7/ADR cells[1].
Web ID
– HY-10815
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H23NOS
References
– [1]Piergentili A, et al. Novel highly potent and selective sigma 1 receptor antagonists related to spipethiane. J Med Chem. 2010;53(3):1261-1269.
CAS Number
– 1204401-49-9
Molecular Weight
– 337.48
Compound Purity
– 99.70
SMILES
– O=C1CC(C2CCN(CC3=CC=CC=C3)CC2)SC4=CC=CC=C41
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Apoptosis;Sigma Receptor
Isoform
– Sigma 1 Receptor
Pathway
– Apoptosis;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
