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Products Details
Product Description
– β3-AR agonist 1 is a highly selective, and orally available agonist of β3-adrenergic receptor (EC50: 18 nM), being inactive to β1-, β2-, and α1A-AR (β1/β3, β2/β3, and α1A/β3>556-fold).
Web ID
– T10523
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H28N4O4S
References
– Wada Y, et al. Discovery of Novel Indazole Derivatives as Orally Available β3-Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects. J Med Chem. 2017 Apr 27;60(8):3252-3265.
CAS Number
– 1283125-73-4
Molecular Weight
– C22H28N4O4S
SMILES
– CC=1C=2C(=CC(OCCNC[C@H](O)C3=CC(NS(=O)(=O)C4CCC4)=CC=C3)=CC2)NN1
Target
– Others
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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