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Products Details
Product Description
– β-Secretase Inhibitor II is a β-Secretase inhibitor. β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.5 μM for Aβ1–42). β-Secretase Inhibitor II can be used for the research of Alzheimer’s disease[1].
Web ID
– HY-136736
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C25H39N3O5
References
– [1]Abbenante, G., et al. Inhibitors of β-Amyloid Formation Based on the β-Secretase Cleavage Site. Biochemical and Biophysical Research Communications. 2000; 268(1), 133–135.
CAS Number
– 263563-09-3
Molecular Weight
– 461.59
SMILES
– O=C(N[C@H](C=O)CC(C)C)[C@H](CC(C)C)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Beta-secretase
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
