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Products Details
Product Description
– β-Secretase Inhibitor I is an extremely potent β-secretase inhibitor with reduced cardiovascular and liver toxicity.
Web ID
– HY-126548
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C18H18F3N5O2S
References
– [1]Tadano G, et al. Discovery of an Extremely Potent Thiazine-Based β-Secretase Inhibitor with Reduced Cardiovascular and Liver Toxicity at a Low Projected Human Dose. J Med Chem. 2019 Oct 24;62(20):9331-9337.
CAS Number
– 1818239-19-8
Molecular Weight
– 425.43
SMILES
– O=C(C1=NC=C(OCF)N=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)S[C@H](C)[C@@H]3F)=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Beta-secretase
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
