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β-NF-JQ1
Price range: 70 CAD through 1,968 CAD
Products Details
Product Description
– β-NF-JQ1 is a PROTAC that recruits aryl hydrocarbon receptor E3 (AhR E3) ligase to target proteins. Using β-NF as an AhR ligand, it targets bromodomain (BRD)-containing proteins and induces AhR and BRD protein interactions. β-NF-JQ1 exhibits potent anticancer activity associated with protein knockdown activity.
Web ID
– T10526
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C45H42ClN5O6S
References
– Ohoka N, et al. Development of Small Molecule Chimeras That Recruit AhR E3 Ligase to Target Proteins. ACS Chem Biol. 2019;14(12):2822-2832.
CAS Number
– 2380000-55-3
Molecular Weight
– C45H42ClN5O6S
Compound Purity
– 0.9945
SMILES
– CC=1C2=C(N3C([C@H](CC(NCCOCCOCCOCC4=CC=C(C=C4)C=5OC=6C(C(=O)C5)=C7C(=CC6)C=CC=C7)=O)N=C2C8=CC=C(Cl)C=C8)=NN=C3C)SC1C
Target
– Others
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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