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β-catenin-IN-37
1,552 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– β-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between β-Catenin and T-cell factor (Tcf), known as β-catenin/Tcf PPI. It effectively inhibits canonical Wnt signaling and impedes the growth of colorectal cancer cells SW480 and HCT116, with IC50 values of 20 μM and 31 μM, respectively.
Web ID
– T39200
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C13H9N9O
References
– Catrow JL, et al. Discovery of Selective Small-Molecule Inhibitors for the β-Catenin/T-Cell Factor Protein-Protein Interaction through the Optimization of the Acyl Hydrazone Moiety. J Med Chem. 2015;58(11):4678-4692.
CAS Number
– 1783856-40-5
Molecular Weight
– C13H9N9O
SMILES
– C(Cn1c2ccccc2c2nc3nonc3nc12)c1nnn[nH]1
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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