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β-Carotene
$50 – $60
Products Details
Product Description
– β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities[1][2][3][4][5].
Web ID
– HY-N0411
Storage Temperature
– -20°C (Powder, protect from light, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C40H56
References
– [1]Tanumihardjo, S.A., Factors influencing the conversion of carotenoids to retinol: bioavailability to bioconversion to bioefficacy. Int J Vitam Nutr Res, 2002. 72(1): p. 40-5.|[2]Leo, M.A., et al. Alcohol, vitamin A, and beta-carotene: adverse interactions, including hepatotoxicity and carcinogenicity. Am J Clin Nutr, 1999. 69(6): p. 1071-85.|[3]Paola Palozza, et al. Prooxidant effects of beta-carotene in cultured cells. Mol Aspects Med. 2003 Dec;24(6):353-62.|[4]AKIFUMI KAWATA, et al. Anti-inflammatory Activity of β-Carotene, Lycopene and Tri-n-butylborane, a Scavenger of Reactive Oxygen Species. In Vivo. 2018 Mar-Apr; 32(2): 255-264.|[5]Yanhong Cui, et al. beta-Carotene induces apoptosis and up-regulates peroxisome proliferator-activated receptor gamma expression and reactive oxygen species production in MCF-7 cancer cells. Eur J Cancer. 2007 Nov;43(17):2590-601.
CAS Number
– 7235-40-7
Molecular Weight
– 536.87264
Compound Purity
– 98.0
SMILES
– CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)=C(C)CCC1
Clinical Information
– Launched
Research Area
– Cancer; Metabolic Disease
Solubility
– DMSO : 1 mg/mL (ultrasonic;warming;heat to 60°C)|THF : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Apoptosis;Endogenous Metabolite;Reactive Oxygen Species
Isoform
– Human Endogenous Metabolite
Pathway
– Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
