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Products Details
Product Description
– β-Aminopropionitrile (BAPN) hydrochloride is a specific, irreversible and orally active lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile hydrochloride targets the active site of LOX or LOXL isoenzymes[1][2].
Web ID
– HY-Y1750A
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C3H7ClN2
References
– [1]Miana M, et al. The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats. Dis Model Mech. 2015 Jun;8(6):543-51.|[2]Yang X, et al. Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells. Oncol Rep. 2013 Feb;29(2):541-8.|[3]Ren W, et al. β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice. Sci Rep. 2016 Jun 22;6:28149.
CAS Number
– 646-03-7
Molecular Weight
– 106.55
SMILES
– NCCC#N.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer, Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite, Monoamine Oxidase
Pathway
– Metabolic Enzyme/Protease, Neuronal Signaling
Product type
– Reference compound
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