α-Conotoxin GID

SKU T80165-5 mg Category Brand:

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Products Details

Product Description

– α-Conotoxin GID is a paralytic peptide neurotoxin that selectively antagonizes nAChR with IC50 values of 5 nM (α7), 3 nM (α3β2), and 150 nM (α4β2). This small, disulfide-rich peptide has potential for chronic pain inhibition. The presence of a C-terminal carboxylate is crucial, as substitution with a C-terminal carboxamide results in loss of activity against α4β2 nAChR. Derived from species of the genus Conus [1] [2] [3].

Web ID

– T80165

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C84H132N30O31S4

CAS Number

– 547741-78-6

Molecular Weight

– C84H132N30O31S4

SMILES

– O=C1[C@]2(N(C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@]3(NC(=O)[C@H](C)NC(=O)[C@]4(N(C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@](CSSC[C@@H](C(O)=O)NC(=O)[C@H]([C@@H](C)C)NC(=O)[C@H](CC5=CN=CN5)N1)(NC(=O)[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CCCNC(=N)N)=O)CC(O)=O)=O)CC(C(O)=O)C(O)=O)=O)CSSC3)[H])CCC4)[H])[H])C[C@H](O)C2)[H]

Product type

– Peptide

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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