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αβ-Tubulin-IN-1
SKU
HY-144132-Get quote
Category Reference compound
Tags Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton, Apoptosis;Microtubule/Tubulin, Cancer
Products Details
Product Description
– αβ-Tubulin-IN-1 is a potent and orally active αβ-Tubulin inhibitor. αβ-Tubulin-IN-1 induces cell cycle arrest at G2/M and efficient apoptosis. αβ-Tubulin-IN-1 inhibits tumor cell migration and Metastasis. αβ-Tubulin-IN-1 shows significant antitumor efficacy in a dose dependent manner[1].
Web ID
– HY-144132
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H19N3O3
References
– [1]Li Y, et al. Structure-Based Design and Synthesis of N-Substituted 3-Amino-β-Carboline Derivatives as Potent αβ-Tubulin Degradation Agents. J Med Chem. 2022 Feb 10;65(3):2675-2693.
CAS Number
– 2478584-74-4
Molecular Weight
– 409.44
SMILES
– C(N1)(C=NC(NCC2=CC=CC(OC3=CC=C(OCO4)C4=C3)=C2)=C5)=C5C6=C1C=CC=C6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Microtubule/Tubulin
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.