(±)-Praeruptorin A

$33$200

Products Details

Product Description

– (±)-Praeruptorin A is the di-esterified product of cis-khellactone (CKL) and the major active ingredient in Peucedani Radix which consists of the dried roots of Peucedanum praeruptorumDunn (Apiaceae). (±)-Praeruptorin A has been widely employed as one of the famous traditional Chinese medicines (TCMs) for the treatment of cough with thick sputum and dyspnea, nonproductive cough and upper respiratory infections for centuries in China. (±)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca2+-influx blocker[1].

Web ID

– HY-N0081

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C21H22O7

References

– [1]Song YL, et al. Metabolic characterization of (±)-praeruptorin A in vitro and in vivo by high performance liquidchromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry. J Pharm Biomed Anal. 2014 Mar;90:98-110.

CAS Number

– 73069-25-7

Molecular Weight

– 386.40

Compound Purity

– 99.31

SMILES

– C/C=C(C)C(O[C@H]1[C@@H](OC(C)=O)C2=C3C(C=CC(O3)=O)=CC=C2OC1(C)C)=O

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Calcium Channel

Isoform

– Calcium Channel

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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