Download Files:
(±)-BI-D
$420 – $2,520
Products Details
Product Description
– (±)-BI-D is an allosteric inhibitor of HIV integrase, acting on the binding site between integrase and LEDGF/p75.
Web ID
– HY-18601
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C25H27NO4
References
– [1]Wang H, et al. HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor. Nucleic Acids Res. 2012 Dec;40(22):11518-30.|[2]Fader LD, et al. Minimizing the Contribution of Enterohepatic Recirculation to Clearance in Rat for the NCINI Class of Inhibitors of HIV. ACS Med Chem Lett. 2014 Apr 16;5(6):711-6.
CAS Number
– 1416258-16-6
Molecular Weight
– 405.49
Compound Purity
– 98.02
SMILES
– OC(C(OC(C)(C)C)C1=C(C(C=CC=C2)=C2N=C1C)C3=CC(CCCO4)=C4C=C3)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : ≥ 100 mg/mL
Target
– HIV;HIV Integrase
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
