Download Files:
Products Details
Product Description
– Bisindolylmaleimide II is a general inhibitor of all PKC subtypes[1].
Web ID
– HY-108604
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C27H26N4O2
References
– [1]Gassel M, et al. The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A. J Biol Chem. 2004 May 28;279(22):23679-90.
CAS Number
– 137592-45-1
Molecular Weight
– 438.52
SMILES
– O=C(C(C1=CNC2=C1C=CC=C2)=C3C4=CN(CCC5N(C)CCC5)C6=C4C=CC=C6)NC3=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– PKC
Pathway
– Epigenetics;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
