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Products Details
Product Description
– EGFR-IN-141 (Compound 8I) functions as an EGFR inhibitor with an IC50 of 2.67 nM. It exhibits cytotoxicity in A549 cancer cells with an IC50 of 13.75 μM. EGFR-IN-141 induces apoptosis and mitochondrial membrane depolarization and shows potential antitumor activity.
Web ID
– T204963
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H15FN8O2S2
CAS Number
– 3054263-27-0
Molecular Weight
– C20H15FN8O2S2
SMILES
– O=C1C=2C=CC=CC2N=CN1CC3=NN=C(SCC(=O)NC4=NC=5C=CC(F)=CC5S4)N3N
Target
– EGFR
Pathway
– Angiogenesis|||Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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