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Products Details
Product Description
– TMX-2138 is a CDKs PROTAC degrader, with IC50 values of 8.7 nM for CDK1/cyclinB, 10.9 nM for CDK2/cyclinA, 7.0 nM for CDK5/p25, and 25.7 nM for CDK9/cyclinT1. It enhances the ubiquitination and degradation of CDKs and is utilized for ovarian cancer research.
Web ID
– T204343
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C40H43BrFN9O11S
CAS Number
– 2488892-07-3
Molecular Weight
– C40H43BrFN9O11S
SMILES
– O=C(N)C=1C(F)=CC=CC1NC2=NC(=NC=C2Br)NC3=CC=C(C=C3)S(=O)(=O)NCCOCCOCCOCCOCCNC4=CC=CC=5C(=O)N(C(=O)C45)C6C(=O)NC(=O)CC6
Target
– FLAP
Pathway
– Cell Cycle/Checkpoint|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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