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Products Details
Product Description
– Gramicidin S 2HCl, is an antibiotic. At concentrations of 40-80 μg/mL, GS can reduce planktonic cell numbers within 20-40 minutes. For established biofilms, it effectively kills cells at concentrations of 100-200 μg/mL without regrowth. This anti-biofilm effect results from peptide transmembrane transport and complexation with intracellular nucleotides (including the alarmone ppGpp). GS demonstrates wide-ranging activity against biofilm-forming, drug-resistant infections caused by E. faecalis, proving its efficacy in endodontic treatment. The successful treatment of persistent infections in two volunteer cases further confirms GS’s potent therapeutic performance. These studies indicate that GS can be applied in certifying compounds used in endodontics.
Web ID
– T203753
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C60H94Cl2N12O10
CAS Number
– 15207-30-4
Molecular Weight
– C60H94Cl2N12O10
SMILES
– O=C1N2[C@](CCC2)([H])C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(N3[C@](CCC3)([H])C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]1CC4=CC=CC=C4)=O)CC(C)C)=O)CCCN)=O)C(C)C)=O)=O)CC5=CC=CC=C5)=O)CC(C)C)=O)CCCN)=O)C(C)C)=O.Cl.Cl
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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