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Products Details
Product Description
– SIAIS562055, a potent cereblon-based SOS1PROTAC, exhibits a dissociation constant (Kd) of 95.9 nM. It effectively degrades SOS1 and inhibits the downstream ERK pathway. SIAIS562055 disrupts the interaction between KRASG12C or KRASG12D and SOS1, with IC50 values of 95.7 nM and 134.5 nM, respectively. This compound demonstrates strong anticancer activity.
Web ID
– T201329
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C49H62F3N7O5S
Molecular Weight
– C49H62F3N7O5S
Target
– Others
Pathway
– GPCR/G Protein|||MAPK|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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