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Products Details
Product Description
– SJYHJ-026 (compound 37) is a pregnane X receptor (PXR) degrader with a DC50 value of 86.6 nM and a maximum degradation efficacy of 66.4%. This compound demonstrates cytotoxicity in SNU-C4 HiBiT-PXR KI cells, with IC50 values of 97.4 μM (24 h) and 99.5 μM (72 h).
Web ID
– T200826
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C60H84N8O11S
Molecular Weight
– C60H84N8O11S
SMILES
– O=C(CC)[O-].O=C(CC)[O-].[Ca+2]
Target
– Beta-Secretase
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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