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Mertansine
Price range: 48 CAD through 525 CAD
Products Details
Product Description
– Mertansine is a tubulin inhibitor and an antibody-conjugable maytansinoid alkaloid. The IC50 of Mertansine against HCT-15 and A431 cells is 0.750 and 0.04nM.
Web ID
– T1992
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C35H48ClN3O10S
Citations
– 1. Wang Y Q, Ji M Y, Wang C. Endoplasmic reticulum-targeted glutathione and pH dual responsive vitamin lipid nanovesicles for tocopheryl DM1 delivery and cancer therapy. International Journal of Pharmaceutics. 2020: 119331.
References
– Whiteman KR, et al. MAbs. 2014 Mar-Apr;6(2): 556-66.
CAS Number
– 139504-50-0
Molecular Weight
– C35H48ClN3O10S
Compound Purity
– 0.9976
SMILES
– CO[C@@H]1C=C/C=C(C)Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCS)[C@@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2
Target
– Others
Pathway
– Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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