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Duvelisib
Price range: 64 CAD through 410 CAD
Products Details
Product Description
– Duvelisib (INK1197, IPI-145) is a selective inhibitor of phosphatidylinositol 3-kinase (PI3K) and p100δ, with effects on p110δ (IC50 value is 0.0025 μM), p110γ (IC50 value is 0.274 μM), p110β (IC50 value is 0.85 μM) and p110α (IC50 value is 1.602 μM).
Web ID
– T1988
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H17ClN6O
Citations
– 1. Xiong W, Jia L, Cai Y, et al.Evaluation of the anti-inflammatory effects of PI3Kδ/γ inhibitors for treating acute lung injury.Immunobiology.2023: 152753.
2. Liu B, Lu T, Ding M, et al.Targeting TTK Inhibits Tumorigenesis of T‐Cell Lymphoma Through Dephosphorylating p38α and Activating AMPK/mTOR Pathway.Advanced Science.2413990
References
– Vito Palombella, Targeting PI3K- δ and PI3K-γ in Inflammation, 2012.
CAS Number
– 1201438-56-3
Molecular Weight
– C22H17ClN6O
Compound Purity
– 0.9974
SMILES
– C[C@H](Nc1ncnc2[nH]cnc12)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1
Target
– Others
Pathway
– PI3K/Akt/mTOR signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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