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Products Details
Product Description
– [Leu144,Arg147]-PLP (139-151) is a modified peptide fragment derived from myelin proteolipid protein (PLP), where leucine and arginine have replaced tryptophan and histidine at positions 144 and 147, respectively. This mutant also functions as a T cell receptor (TCR) antagonist, inhibiting the activation of encephalitogenic Th1 clones in vitro. Additionally, [Leu144,Arg147]-PLP (139-151) can impede the progression of experimental autoimmune encephalomyelitis (EAE).
Web ID
– TP2675
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C67H110N20O17
CAS Number
– 188859-65-6
Molecular Weight
– C67H110N20O17
SMILES
– C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)CCCCN)=O)CC(O)=O)(=O)[C@H]2N(C([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CN=CN3)N)=O)CO)=O)CC(C)C)=O)=O)CCCCN)=O)CC(C)C)=O)CC(C)C)=O)=O)CCCNC(=N)N)=O)CCC2
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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