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TC14012 acetate
Price range: 123 CAD through 1,744 CAD
Products Details
Product Description
– TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is also a potent CXCR7 agonist with an EC50 of 350 nM for recruiting β-arrestin 2 to CXCR7. TC14012 has anti-cancer activity and anti-HIV activity.
Web ID
– TP2112L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C92H144N34O21S2
References
– H Tamamura, et al. Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1897-902.
Molecular Weight
– C92H144N34O21S2
Compound Purity
– 0.9833
SMILES
– [H]N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CSSC[C@@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)NC([C@H](NC([C@@H](NC([C@@H](NC([C@@H]2CCCN2C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CC3=CC=C(C=C3)O)=O)CCCNC(N)=O)=O)CCCCN)=O)CCCNC(N)=O)=O)=O)CC4=CC=C(C=C4)O)=O)CCCNC(N)=N)=O)CCCNC(N)=O)=O)=O)CC5=CC6=CC=CC=C6C=C5)=O)CCCNC(N)=N)=O)CCCNC(N)=N.CC(O)=O
Pathway
– Autophagy|||GPCR/G Protein|||Immunology/Inflammation
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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