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Urantide
534 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– Selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3). Blocks hU-II induced contractions in thoracic aorta ex vivo. Exhibits no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Behaves as a partial agonist in a calcium mobilization assay (in CHO cells expressing hUT receptors).
Web ID
– TP2106
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C51H66N10O12S2
Citations
– 1. Sun J, Zhou J, Sun S, et al.Protective effect of urotensin II receptor antagonist urantide and exercise training on doxorubicin-induced cardiotoxicity.Scientific Reports.2023, 13(1): 1279.
References
– Patacchini et al (2003) Urantide: an ultrapotent urotensin II antagonist peptide in the rat aorta. Br.J.Pharmacol. 140 1155 PMID:
CAS Number
– 669089-53-6
Molecular Weight
– C51H66N10O12S2
SMILES
– C(C=1C=2C(NC1)=CC=CC2)[C@H]3NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@@H](NC([C@H](CC(O)=O)N)=O)C(C)(C)SSC[C@@H](C(N[C@@H](C(C)C)C(O)=O)=O)NC(=O)[C@H](CC5=CC=C(O)C=C5)NC(=O)[C@H](CCCN)NC3=O
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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