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ELA-21 (human)
330 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– High affinity apelin receptor agonist. Binds apelin receptors in left ventricle from normal and pulmonary arterial hypertensive (PAH) hearts (pKi values are 9.31 and 9.46, respectively). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.
Web ID
– TP2096
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C112H184N40O25S3
References
– Yang et al (2017) Elabela/Toddler is an endogenous agonist of the apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary arterial hypertension. Circulation 135 1160 PMID:
CAS Number
– 2245073-05-4
Molecular Weight
– C112H184N40O25S3
SMILES
– C(N[C@H](C(=O)N1[C@H](C(O)=O)CCC1)CC2=CC=CC=C2)(=O)[C@H]3N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CN=CN4)NC([C@@H](NC(=O)[C@H]5N(C([C@@H](NC(=O)[C@H]6NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC([C@@H](NC([C@H](CC7=CN=CN7)NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)N)=O)CCCNC(=N)N)=O)CCCCN)=O)=O)CC(N)=O)=O)CSSC6)CCSC)=O)CCC5)CC(C)C)=O)=O)CO)=O)CCCNC(=N)N)=O)C(C)C)=O)CCC3
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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