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α-Conotoxin MII
158 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– α-Conotoxin MII is a highly potent and selective competitive antagonist for α3β2 subunit-containing nicotinic receptors (IC50 = 0.5 – 3.5 nM at α3β2 expressed in Xenopus oocytes). Also potently blocks β3-containing neuronal nicotinic receptors. Displays > 200-fold selectivity for α3β2 over α2β2, α4β2 and α3β4.
Web ID
– TP2063
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C67H103N23O22S4
References
– Cartier et al (1996) A new α-conotoxin which targets α3β2 nicotinic acetylcholine receptors. J.Biol.Chem. 271 7522 PMID:
CAS Number
– 175735-93-0
Molecular Weight
– C67H103N23O22S4
SMILES
– O=C1N2[C@@](CCC2)(C(=O)N[C@@H](C(C)C)C(=O)N[C@@]3(C(=O)N[C@@H](CC4=CN=CN4)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC5=CN=CN5)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(N)=O)CSSC[C@@](C(=O)N[C@@H](CO)C(=O)N[C@H]1CC(N)=O)(NC(=O)[C@@H](NC(CN)=O)CSSC3)[H])[H])[H]
Pathway
– Neuroscience
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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