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187-1, N-WASP inhibitor
1,000 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– Inhibits neural Wiskott-Aldrich syndrome protein (N-WASP) by stabilizing the autoinhibited state of the protein. Blocks phosphatidylinositol 4,5-bisphosphate (PIP2)-stimulated actin assembly (IC50 ~ 2 μM) but does not directly inhibit actin polymerization.
Web ID
– TP1977
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C96H122N18O16
References
– Suetsugu et al (2001) Identification of another actin-related (Arp) 2/3 complex binding site in neural Wiskott-Aldrich syndrome protein (N-WASP) that complements actin polymerization induced by the Arp2/3 complex activating (VCA) domain of N-WASP. J.Biol.Chem. 276 33175 PMID:
CAS Number
– 380488-27-7
Molecular Weight
– C96H122N18O16
SMILES
– O=C1N2C(C(=O)N[C@H](CC3=CC=CC=C3)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N5[C@@](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CC6=CC=CC=C6)C(=O)N7C(C(=O)N[C@H](CC8=CC=CC=C8)C(=O)N[C@@H](CC9=CC=CC=C9)C(=O)N%10[C@@](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1CC%11=CC=CC=C%11)(CCC%10)[H])(CCC7)[H])(CCC5)[H])(CCC2)[H]
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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