[Pyr1]-Apelin-13

SKU TP1260-1 mg Category Brand:

Price range: 142 CAD through 2,176 CAD

Products Details

Product Description

– [Pyr1]-Apelin-13 ([pGlu1]-Apelin-13) is a potent and selective endogenous Apelin receptor (APJ) agonist.

Web ID

– TP1260

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C69H108N22O16S

Citations

– 1. Song K, Yang X, An G, et al.Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.Nature Communications.2022, 13(1): 1-17. 2. Shi N, Wang Y, Xia Z, et al.The regulatory role of the apelin/APJ axis in scarring: Identification of upstream and downstream mechanisms.Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease.2024: 167125.

References

– Serpooshan V, et al. [Pyr1]-Apelin-13 delivery via nano-liposomal encapsulation attenuates pressure overload-induced cardiac dysfunction. Biomaterials. 2015 Jan;37:289-98.

CAS Number

– 217082-60-5

Molecular Weight

– C69H108N22O16S

Compound Purity

– 1

SMILES

– CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC[C@@H]1CCCN1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O

Pathway

– GPCR/G Protein

Product type

– Peptide

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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