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Product Description
– Glucopiericidin A is a natural piperidine-based compound found in marine-derived Streptomyces strains. It serves as a chemical probe for glucose transporter proteins (GLUT) and can inhibit glycolysis. When combined with Piericidin A (PA), it synergistically inhibits ATP-dependent filopodia formation, yet has no effect alone. Glucopiericidin A induces apoptosis by increasing PRDX1, thereby reducing reactive oxygen species (ROS) levels, and also demonstrates potent antitumor activity in ACHN mouse xenografts.
Web ID
– TN9037
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C31H47NO9
CAS Number
– 108073-65-0
Molecular Weight
– C31H47NO9
SMILES
– O([C@H]([C@@H](/C=C(/C=C/C/C(=C/CC=1N=C(OC)C(OC)=C(O)C1C)/C)C)C)/C(=C/C)/C)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O
Pathway
– Apoptosis|||Antibody-drug Conjugate/ADC Related
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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