12-Deoxyphorbol 13-palmitate

SKU TN8147-10 mg Category Brand:

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Products Details

Product Description

– 12-Deoxyphorbol 13-palmitate, a monomer derived from the roots of Euphorbia fischeriana, exhibits notable antitumor activity. This compound induces cell cycle arrest and apoptosis in gastric cancer cells by modulating key cell cycle regulators, such as cyclin B, cyclin A, and CDC2. Additionally, 12-Deoxyphorbol 13-palmitate significantly diminishes liver fibrosis by targeting APOL2 and impairing the APOL2–SERCA2–PERK–HES1 signaling pathway.

Web ID

– TN8147

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C36H58O6

CAS Number

– 66583-59-3

Molecular Weight

– C36H58O6

SMILES

– O(C(CCCCCCCCCCCCCCC)=O)[C@@]12[C@@](C1(C)C)([C@]3([C@](O)([C@H](C)C2)[C@]4([C@](O)(CC(CO)=C3)C(=O)C(C)=C4)[H])[H])[H]

Pathway

– Cell Cycle/Checkpoint|||Apoptosis

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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