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[12]-Dehydrogingerdione
3,149 CAD
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Products Details
Product Description
– [12]-Dehydrogingerdione is a natural product found in ginger that has anti-neuroinflammatory activity, possibly by inhibiting the Akt/IKK/IκB/NF-κB pathway and promoting the Nrf-2/HO-1 pathway to prevent neuroinflammation. 12-Dehydrogingerdione can inhibit the production of NO, IL-6, and PGE2 in LPS-stimulated Raw 264.7 cells.
Web ID
– TN5754
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H34O4
References
– Zhao D, et al. Anti-neuroinflammatory Effects of 12-Dehydrogingerdione in LPS-Activated Microglia through Inhibiting Akt/IKK/NF-κB Pathway and Activating Nrf-2/HO-1 Pathway. Biomol Ther (Seoul). 2019 Jan 1;27(1):92-100.
CAS Number
– 99742-05-9
Molecular Weight
– C23H34O4
SMILES
– C(=C/C(=CC(CCCCCCCCCCC)=O)O)C1=CC(OC)=C(O)C=C1
Pathway
– Others
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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