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Product Description
– Gelsevirine, a novel STING-specific inhibitor, is an alkaloid from Gelsemium elegans with anxiolytic and antiproliferative activities that inhibits interferon and inflammatory cytokine induction in macrophages exposed to STING agonists, and attenuates STING-related inflammation in sepsis.
Web ID
– TN1678
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H24N2O3
References
– Cytotoxic effects of alkaloidal compounds from Gelsemium elegans Benth on the tumor cells of digestive system in vitroStrait Pharmaceutical Journal, 2010 , 22 (3) :197-200.
CAS Number
– 38990-03-3
Molecular Weight
– C21H24N2O3
Compound Purity
– 0.97
SMILES
– [H][C@]12CO[C@@H]3C[C@H]1[C@@]1(CN(C)[C@@]2([H])[C@]1([H])[C@@]31C(=O)N(OC)c2ccccc12)C=C
Pathway
– Immunology/Inflammation
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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