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Products Details
Product Description
– Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE(2) and the expression of respective enzyme iNOS and COX-2 through the suppression of I-kappaB-alpha degradation and nuclear translocation of p65 subunit of NF-kappaB. It also exhibits antiallergic effects without affecting the viability of bone marrow-derived mast cells.
Web ID
– TN1009
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H28O7
References
– In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii.Bioorg Med Chem Lett. 2009 Feb 1;19(3):937-40.
CAS Number
– 1134188-26-3
Molecular Weight
– C23H28O7
SMILES
– [H][C@@]12CO[C@H](c3cc(OC)c(OC)c(OC)c3)[C@]1([H])CO[C@H]2c1cc(OC)cc(OC)c1
Pathway
– NF-κB|||GPCR/G Protein|||Immunology/Inflammation
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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