Camptothecin-d5

SKU T89650-10 mg Category Brand:

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Products Details

Product Description

– Camptothecin-d5 is a deuterated derivative of Camptothecin (CPT), an alkaloid and an inhibitor of DNA topoisomerase I (Topo I) with an IC50 value of 679 nM. Camptothecin (CPT) exhibits potent antitumor activity against colorectal, breast, lung, and ovarian cancers by modulating the expression pattern of miRNA and regulating the activity of hypoxia-inducible factor-1α (HIF-1α) in human cancer cells.

Web ID

– T89650

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H16N2O4

CAS Number

– 1329616-37-6

Molecular Weight

– C20H16N2O4

SMILES

– [C@](C([2H])([2H])[2H])([C@]1(O)C2=C(C(=O)N3C(=C2)C=4C(C3)=CC=5C(N4)=CC=CC5)COC1=O)([2H])[2H]

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– Isotope products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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