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PNU112455A hydrochloride
Price range: 62 CAD through 1,712 CAD
Products Details
Product Description
– PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.
Web ID
– T8230
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C10H12ClN5O2S
Citations
– 1. Jiang L, Yu Y, Li Z, et al.BMS-265246, a Cyclin-Dependent Kinase Inhibitor, Inhibits the Infection of Herpes Simplex Virus Type 1.Viruses.2023, 15(8): 1642.
References
– Clare PM, et al. The cyclin-dependent kinases cdk2 and cdk5 act by a random, anticooperative kinetic mechanism. J Biol Chem. 2001 Dec 21;276(51):48292-9.
CAS Number
– 21886-12-4
Molecular Weight
– C10H12ClN5O2S
Compound Purity
– 0.9858
SMILES
– Cl.Nc1cc(Nc2ccc(cc2)S(N)(=O)=O)ncn1
Pathway
– Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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