Spinoxin

SKU T80530-5 mg Category Brand:

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Products Details

Product Description

– Spinoxin, a 34-residue peptide neurotoxin extracted from the venom of Heterometrus spinifer, is characterized by four disulfide bridges. It acts as a potent inhibitor of the Kv1.3 potassium channel with an IC 50 value of 63 nM. This compound is regarded as a promising molecular target for the diagnosis and treatment of a range of autoimmune disorders and cancers [1].

Web ID

– T80530

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C147H236N48O46S9

CAS Number

– 752984-66-0

Molecular Weight

– C147H236N48O46S9

SMILES

– O=C1N2[C@@](CCC2)(C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@]3(C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@]4(C(=O)N[C@@H](CCCCN)C(=O)N[C@@]5(C(=O)N[C@@H](CC6=CC=C(O)C=C6)C(=O)NCC(=O)N[C@H](C(N)=O)CSSC[C@@]1(NC(=O)CNC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCSC)NC(=O)[C@](CSSC5)(NC(=O)[C@]7(N(C(=O)[C@H](CO)NC(=O)[C@H](CC8=CC=C(O)C=C8)NC(=O)[C@](CSSC4)(NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CCCNC(=N)N)=O)CSSC3)[H])CCC7)[H])[H])[H])[H])[H])[H])[H])[H])[H]

Pathway

– Membrane transporter/Ion channel

Product type

– Peptide

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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