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Products Details
Product Description
– α-Conotoxin BuIA is a paralytic peptide neurotoxin that acts as a competitive antagonist of nicotinic acetylcholine receptors (nAChR), with inhibitory concentration 50 (IC50) values of 0.258 nM for α6/α3β2, 1.54 nM for α6/α3β4, and 5.72 nM for α3β2. It serves to differentiate between nAChRs containing the β2- and β4-subunits and selectively inhibits αxβ2 nAChRs, exhibiting a potency hierarchy of α6>α3>α2>α4 [1].
Web ID
– T80166
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C54H82N14O16S4
CAS Number
– 846539-62-6
Molecular Weight
– C54H82N14O16S4
SMILES
– O=C1[C@]2(N(C(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CO)NC(=O)[C@]3(NC(=O)[C@@H](NC(CN)=O)CSSC[C@](NC(=O)[C@]4(N1CCC4)[H])(C(=O)N[C@@H](C)C(=O)N[C@@H]([C@H](C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC5=CC=C(O)C=C5)C(=O)N[C@H](C(N)=O)CSSC3)[H])[H])[H])CCC2)[H]
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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